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2012年9月14日 星期五

Understanding Burkitt's Lymphoma


Burkitt's lymphoma is a rare kind of non-Hodgkin's lymphoma (NHL) that originates in the B-lymphocytes, a particular type of cells in the immune system that produce antibodies. The disease was described for the first time in 1956 by Denis Parsons-Burkitt, a surgeon who was working in central Africa.

Burkitt's lymphoma is an aggressive type of NHL that mainly occurs in children. There are primarily two distinct types of Burkitt's lymphoma, and these are the sporadic type and the endemic type. Endemic Burkitt's lymphoma is limited to equatorial Africa that has a very high incidence of this disease. The striking characteristics of endemic variety are large tumors that form in the jaw and abdominal regions. Sporadic variety of this disease occurs in other parts of world other than central Africa. This variety involves B-cells in the bone marrow and abdomen.

Often referred to as B-cell lymphoma or B-cell leukemia, this disease originates primarily due to B-cells getting infected with Epstein-Barr virus. Other factors that aid in the occurrence of the disease include inheritance patterns and chromosomal defects. Symptoms of this disease are dependent on the site of origin of this disease. Some common symptoms observed in this disease include painful swelling of the affected area, nausea, vomiting, fever and anemia. Since the malignancy grows rapidly, the health of child also deteriorates rapidly. Diagnosis of this disease is possible through bone marrow aspiration and biopsy of the affected region. Other diagnostic procedures include determining blood counts, microscopic examination of spinal fluid and CT scans.

Even though, Burkitt's lymphoma is a highly invasive cancer, it is also one of the more curable forms of lymphoma. The most common therapeutic approach is chemotherapy. Some of the drugs that are used for treatment include doxorubicin, cyclophosphamide, vincristine, methotrexate, cytarabine, ifosfamide and etoposide. However, the success of the therapy depends on the stage at which the disease is diagnosed. Other therapeutic approaches include bone marrow transplantation (BMT), immunotherapy using monoclonal antibodies and radiation therapy.




Check Out More Articles:

Lymphoma Misdiagnosis Story, Medical Research on Muscle Building,

What a Medical Research Center Does?,





This post was made using the Auto Blogging Software from WebMagnates.org This line will not appear when posts are made after activating the software to full version.

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2012年9月13日 星期四

Back Pain and Sciatica Relief - Understanding Osteomyelitis


Osteomyelitis, as it relates to back pain and sciatica, is an infection of the bone or bone marrow affecting the vertebral bodies of the spine. Osteomyelitis may be debilitating, disabling, and devastating, both physically and psychologically. The infection, usually a staph infection in adults (staphylococcus aureus), may in extreme cases cause death. Osteomyelitis is often difficult to diagnose and may go undetected for weeks, months, and even years. Unless properly diagnosed by a medical practitioner specializing in orthopedic medicine and infectious diseases, usually with blood tests focusing on the sedimentation rate, a bone biopsy to identify the nature of the infection, a radiologic examination to document certain changes in the bone, and magnetic resonance imaging (MRI) focusing on "hot spots," the prognosis may not good. Back pain and sciatica associated with osteomyelitis can range from a mild ache to a chronic and/or acute level of pain, completely incapacitating the individual. In this stage, without medical intervention pain relief is impossible.

The staphylococcus aureus bacteria may be introduced via a cut or sore on the body, usually in close proximity to bone, or as the result of a compound fracture (bone breaking through the skin). The bacteria may also be introduced during surgery, as the result of a spinal block or some other related procedure, or any other situation or circumstance where staph finds its way into the body. In such cases, it is vital that the patient confer with their medical practitioner to insure that the proper tests are ordered.

Common symptoms of osteomyelitis include:

o Malaise and a general weakness, often mistaken for chronic fatigue syndrome in the early stages.

o Sweating due to fever or chills, particularly "night sweats."

o Pain deep within the bone, usually an ache or throbbing sensation.

o Increased pain when pressure is applied around the area of injury or when the patient is standing,

o The area adjacent to a fracture or surgery site becomes swollen and inflamed.

o The skin around the affected area turns red and/or pus drains from the wound.

Osteomyelitis often requires intensive and prolonged antibiotic therapy. The antibiotic therapy, most commonly vancomycin, is administered intravenously and helps fight the infection, thus avoiding greater destruction of the bone and relieving the inflammation often at the root of the back pain and sciatica.

In severe cases of osteomyelitis, surgery may be required. The surgery is often a debridement, the removal of the infected and dead (necrotic) bone and tissue associated with the infection. In the worst case, osteomyeltitis may lead to the loss of a limb, significant damage to the spine and associated musculature and connective tissue, and even death...as noted above.

If the staph infection is discovered early enough, the prognosis is quite good. The back and sciatic nerve pain (sciatica) associated with osteomyelitis usually abates. However, if the infection goes undiagnosed and untreated for a long period of time, the back pain and sciatica associated with it may be totally debilitating and disabling. Additionally, if the patient fails to seek medical attention, the damage to the body may be profound and unalterable, permanent.

Finally, if you have the symptoms mentioned above, and very often the malaise and night sweats in conjunction with the back pain and sciatica will point you in the right direction...seek medical attention immediately. Why suffer when you don't have to? Osteomyelitis, and the associated back pain complex, in this case back pain and sciatica, is treatable and the prognosis can be quite good.




For further information, including an awesome book entitled The 7 Day Back Pain Cure, and an intelligent program of treatment for neck pain, back pain, and sciatica, what I refer to as the "back pain complex" click the link below:

http://www.TheBackPainInstitute.org

For additional resources, articles, and videos dealing with neck pain, back pain, and sciatica, including additional treatment plans and a community for support...

Go to:

http://www.UltimateBadBackStrategies.com

John P. Zajaros, Sr., The Bad Back Guy





This post was made using the Auto Blogging Software from WebMagnates.org This line will not appear when posts are made after activating the software to full version.

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2012年8月4日 星期六

Understanding Burkitt's Lymphoma


Burkitt's lymphoma is a rare kind of non-Hodgkin's lymphoma (NHL) that originates in the B-lymphocytes, a particular type of cells in the immune system that produce antibodies. The disease was described for the first time in 1956 by Denis Parsons-Burkitt, a surgeon who was working in central Africa.

Burkitt's lymphoma is an aggressive type of NHL that mainly occurs in children. There are primarily two distinct types of Burkitt's lymphoma, and these are the sporadic type and the endemic type. Endemic Burkitt's lymphoma is limited to equatorial Africa that has a very high incidence of this disease. The striking characteristics of endemic variety are large tumors that form in the jaw and abdominal regions. Sporadic variety of this disease occurs in other parts of world other than central Africa. This variety involves B-cells in the bone marrow and abdomen.

Often referred to as B-cell lymphoma or B-cell leukemia, this disease originates primarily due to B-cells getting infected with Epstein-Barr virus. Other factors that aid in the occurrence of the disease include inheritance patterns and chromosomal defects. Symptoms of this disease are dependent on the site of origin of this disease. Some common symptoms observed in this disease include painful swelling of the affected area, nausea, vomiting, fever and anemia. Since the malignancy grows rapidly, the health of child also deteriorates rapidly. Diagnosis of this disease is possible through bone marrow aspiration and biopsy of the affected region. Other diagnostic procedures include determining blood counts, microscopic examination of spinal fluid and CT scans.

Even though, Burkitt's lymphoma is a highly invasive cancer, it is also one of the more curable forms of lymphoma. The most common therapeutic approach is chemotherapy. Some of the drugs that are used for treatment include doxorubicin, cyclophosphamide, vincristine, methotrexate, cytarabine, ifosfamide and etoposide. However, the success of the therapy depends on the stage at which the disease is diagnosed. Other therapeutic approaches include bone marrow transplantation (BMT), immunotherapy using monoclonal antibodies and radiation therapy.




Check Out More Articles:

Lymphoma Misdiagnosis Story, Medical Research on Muscle Building,

What a Medical Research Center Does?,





This post was made using the Auto Blogging Software from WebMagnates.org This line will not appear when posts are made after activating the software to full version.

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2012年7月25日 星期三

Back Pain and Sciatica Relief - Understanding Osteomyelitis


Osteomyelitis, as it relates to back pain and sciatica, is an infection of the bone or bone marrow affecting the vertebral bodies of the spine. Osteomyelitis may be debilitating, disabling, and devastating, both physically and psychologically. The infection, usually a staph infection in adults (staphylococcus aureus), may in extreme cases cause death. Osteomyelitis is often difficult to diagnose and may go undetected for weeks, months, and even years. Unless properly diagnosed by a medical practitioner specializing in orthopedic medicine and infectious diseases, usually with blood tests focusing on the sedimentation rate, a bone biopsy to identify the nature of the infection, a radiologic examination to document certain changes in the bone, and magnetic resonance imaging (MRI) focusing on "hot spots," the prognosis may not good. Back pain and sciatica associated with osteomyelitis can range from a mild ache to a chronic and/or acute level of pain, completely incapacitating the individual. In this stage, without medical intervention pain relief is impossible.

The staphylococcus aureus bacteria may be introduced via a cut or sore on the body, usually in close proximity to bone, or as the result of a compound fracture (bone breaking through the skin). The bacteria may also be introduced during surgery, as the result of a spinal block or some other related procedure, or any other situation or circumstance where staph finds its way into the body. In such cases, it is vital that the patient confer with their medical practitioner to insure that the proper tests are ordered.

Common symptoms of osteomyelitis include:

o Malaise and a general weakness, often mistaken for chronic fatigue syndrome in the early stages.

o Sweating due to fever or chills, particularly "night sweats."

o Pain deep within the bone, usually an ache or throbbing sensation.

o Increased pain when pressure is applied around the area of injury or when the patient is standing,

o The area adjacent to a fracture or surgery site becomes swollen and inflamed.

o The skin around the affected area turns red and/or pus drains from the wound.

Osteomyelitis often requires intensive and prolonged antibiotic therapy. The antibiotic therapy, most commonly vancomycin, is administered intravenously and helps fight the infection, thus avoiding greater destruction of the bone and relieving the inflammation often at the root of the back pain and sciatica.

In severe cases of osteomyelitis, surgery may be required. The surgery is often a debridement, the removal of the infected and dead (necrotic) bone and tissue associated with the infection. In the worst case, osteomyeltitis may lead to the loss of a limb, significant damage to the spine and associated musculature and connective tissue, and even death...as noted above.

If the staph infection is discovered early enough, the prognosis is quite good. The back and sciatic nerve pain (sciatica) associated with osteomyelitis usually abates. However, if the infection goes undiagnosed and untreated for a long period of time, the back pain and sciatica associated with it may be totally debilitating and disabling. Additionally, if the patient fails to seek medical attention, the damage to the body may be profound and unalterable, permanent.

Finally, if you have the symptoms mentioned above, and very often the malaise and night sweats in conjunction with the back pain and sciatica will point you in the right direction...seek medical attention immediately. Why suffer when you don't have to? Osteomyelitis, and the associated back pain complex, in this case back pain and sciatica, is treatable and the prognosis can be quite good.




For further information, including an awesome book entitled The 7 Day Back Pain Cure, and an intelligent program of treatment for neck pain, back pain, and sciatica, what I refer to as the "back pain complex" click the link below:

http://www.TheBackPainInstitute.org

For additional resources, articles, and videos dealing with neck pain, back pain, and sciatica, including additional treatment plans and a community for support...

Go to:

http://www.UltimateBadBackStrategies.com

John P. Zajaros, Sr., The Bad Back Guy





This post was made using the Auto Blogging Software from WebMagnates.org This line will not appear when posts are made after activating the software to full version.

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